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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed327c10c662d119503eda00188cea711f07207f17a7637c5c72b8fb173a0589' 
  AND token = 'gzs7U1G1CS3krENZXeaKJk1t6OFx/txc9oFd+LJKkCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}