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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b03efd14ec67c6513cbd983f7349f93a7eb29914d249e653a120e0c73f37b1' 
  AND token = 'c3FunXjQyIc4Rw7w+pyP16fLy6RoCcBJiUcUFx9asQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}