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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '876154249d61b935a229e10d31987802a78d5a244864d7b9fa4829a6007faae6' 
  AND token = 'DLuJ9uzUiA8ZXEvuIsnZY+uXJpwe9oKeWZpLTHUEYLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}