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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02e2a537c107e5af3a6656a6252cb4e4e43d35de6218df1b9bcb9b6f32c9a99f' 
  AND token = 'r3IxMgctKgcxR0O9IIxb6g/TDqfKMtBPBYBxZP+W3cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}