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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b7d8bed3713a10f6df11f30d0767cee1ddffecf6b42c1473abe256fb1bb5eb' 
  AND token = '4JKBc//XiQuvdvZR4BQ0uehCRxprEdKC7RuVzM2qJAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}