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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e01c61ca7835c2437550fa0f5cadc69d5491634ea84cd88f0da88a67766c179' 
  AND token = 'pOtVkyh7h+FAsGBW0/r5c4xJo28dfn7CzE4xndyqnec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}