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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b9135b5f7ac807507b9f70903275dce6918da42ab3935d904566b6947b50e3' 
  AND token = 'IHg0q8dzTrmDd1bQJ+4+R2IReiI01Ho/vHmFc00iHgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}