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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b055e69bcf9fa53e74dbbaed3369931a28d6a2a7d4b8ca13b9a115ce9c858800' 
  AND token = '3OZm/KxNDCeA5aOufcpgDkkMCxKIc/EVthwUqZ1LOCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}