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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84172b3a39b99af5fcdb519a843fda578d01fdc4d06d7125df386bd9a07b6af3' 
  AND token = 'OmrB/fmsi0AJuHGW1cCP0MhCTIQHz/y1AYv/8Ebem4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}