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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7b7c653d700e424d4a13674695c492dd1a0bc489b5bba3b7b4b274957283de' 
  AND token = 'NgKjYEz26vlY7p7CNmIDvwAowxZq63qZC7ZGF5wm7fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}