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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d51a9989a7b59e1a4d27d4188b1f2752441bf4969887a6b587a00b38967816a' 
  AND token = 'GOoLb6T7essRRTk6DuCDfgAa+5ygKQ0TKCZUVa8+MGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}