SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1058f629d109d75ef1c88e4e8739978c4daa1c59453341e6e9ef29e08385324' 
  AND token = 'QSll71guhr7AAkSqaUN+ehGqiCz1Hp2v7gop4xPgfSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}