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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10343eee23dc37a62f9be84c4dba24d6def1347ba51162fe34a56347b88af119' 
  AND token = 'r1B0jwGuwgtEOtSDTPtCn8fi2X7te2Gz27GfRDNF9vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}