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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2611805fec4674e3cf430abf5c18db46db69e07491c3f5e5173e246a0d91046a' 
  AND token = 'qYdkCBL26tDY8a7XsYwj0atujYgRoWQUSOKK5TJ84GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}