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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8309860ad28aac6e0ad20012ccbce0cd13594f4778844a13c65ae7f5d9e4f8bb' 
  AND token = 'WZn6cj1z9Tqwgi0psN2DPx+A6dCoPkNDZ+gaiv0o9YQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}