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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee0a899f40558e4d0126080ab849696fd08400e230b76e9c0652b8bd941f20a' 
  AND token = 'Q0M6mGFWu7IipGdOglmd0SLPLgoZZY3Y2gB+/xAbI5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}