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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b2194733f58265b3553b2a96af5e4f03a06251e1783b3454186de4983e73da' 
  AND token = '3gHZXcz+AwQNdviyaM3C9c7zAuWKs7F3tQX3IWgYjvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}