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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0061cf7ee6364023dadb47eae4f1f154285e79333677c0518a0d9a5d92bfdca' 
  AND token = '5u/AuZf7ltEluK2PEQCfwEPuV1KoJnISk6yfK+GQe/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}