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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd746cfa4d39c47b7490c90137c404261791153ca96757e5d72b71d6b7f3ae5f0' 
  AND token = 'Fj6pZLi+hROGRmfeCpOEZKlpxMKO9jQd49MHD+0Dy10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}