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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f10fee9281fe0f34e6ce7acef0c7025582b1679c79010d58fccce22f4ceab49' 
  AND token = 'S//DWXi5nKZKxweb7xsDG9Fs9rPGTS9fzQosbSS7gx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}