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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5c64d3046f9d25f1bba6ccad6070d3bce8bdc0539aebc48210749c2295692d' 
  AND token = 'pKlcYfq8Zfl+sX1kNfuymrlPn3rI7j3/TgEmV5alUNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}