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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9e24d4dfd6a6a3877aa5ed2186a974627975e753d53855de22d4b90dddd27d' 
  AND token = 'df2117UmHEg+zAS9C9qm4tiSnEXEYGPMSef6wa3Gxv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}