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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7818cb9739cf26f351e38fee0a3a9b665b7522d9921ba38bb1348d3c0354ab76' 
  AND token = 'ttQ4jpZokCKCtUZQ/8aG7tXSN5B/yA1Efm6oDWDWgmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}