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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b14f81c6213c48808aee2b4dbf0beee1efe206a2c910f57217152944aea5bb9' 
  AND token = 'fOe+rpqJe4EZU6d6YEcWOZsDcF+t43P06moACLZcxm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}