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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045a95b74048bc4bd6852a4d5a9b42b0f1e51e9b3db61ab1bfeb2af8e190c3b8' 
  AND token = 'RPCOZnEwWoTq7dayDMS3yUyZeuiat2OWA12Moq/FG7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}