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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65e34542a290138a8371a2a10f81a9de4fc6741813d66ff6aaea0718fca8c12' 
  AND token = 'dZ+nnZjzRhjlWK/iJh+Xm0ci43cly5gW7EKeuW8SVgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}