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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4070496c1fe25fe6b661d957897fb712067cc9086c38cb0254f60dc7fb28d8e7' 
  AND token = 'sPv91qtmO7RDI1XaHWcyfwaeITC1sLZ16Fj3RRdn+i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}