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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e65464f30a51a25922b9208c769ce574bcdc29f7d1ecee5a6a1fa8af861fa13' 
  AND token = 'KDwN7WQhYvn6rn8RxDwJ1TjexyMMY5+qsYgzW1QMqqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}