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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c64f1024d0d2db202216407189b624d8d773022c3da8950d27b15caadfe72c1' 
  AND token = 'w2UcRa47NI1RJfadrlp42wZwI/+C4+SDYuhs+VSxsKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}