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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3bcfa6fe7784ce4f2abec1f4beb3172f287300f32285e5f230d0e5b8860b750' 
  AND token = 'ZWObkr+KIYUtUS/apGucWnHcVM4TzL0Cr3KHsr6qvpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}