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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac76522f6e2c302d7d10f3355f1e142a4a172481151c4bfd8ba9b4ab4c2ff9a0' 
  AND token = '3ekD4Cu60R0QzpSP6gGoGcMwHSyOIb7HCld/BstUMX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}