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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312aae50086e0c6e8b6331f16c65808ac2ad76178b40194b6a8cd5347d27a7da' 
  AND token = '+ttjSG7VDDfwREpTjv4fO/qccg1d9P+ISgkTRbZSMyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}