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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c297023a8028627b52a9db10c10a01e473983e1db7efe036fc9be364de05bb70' 
  AND token = 'R3TSz/9cfqLFE2zH3u9w/Qme2D9KTQ3aOSCY5LdD7fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}