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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14c827864720a03349e0c39a39a746a0c00ded1edb059d5c2cf84fc3b4b9df7' 
  AND token = 'QUZhBsSxOftzOx+Fr8Vos3JaXoSa9ZZ/f4ODb1LNziA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}