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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2149badf07eb7816025d05e660d069f5ad9144a5a951e1c867efa5b74de45471' 
  AND token = 'pWWHt6o92T9ecHWU45Cyjql4G9Qz6nAMYmFuS03jOi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}