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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7bb246aa062f12fb9cef661f959f48f8410705adcc20f4c9f3f9395824d234' 
  AND token = 'KB7KASj2/8VcaKU3ZLT7eVNP6DGL2vakQN6lmEOsmt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}