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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4dcd8ab42771ecd4309186f3a9d5c4c33121818ecec973d63397b38ac56b133' 
  AND token = 'i9bCSyq3bNJ4pwLGYfXaTir1lORCFzjCJBrc7xj9AlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}