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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5a72d96b8f975cde0f78b79827b1ac583ad2f14fbef02b431c0c491338e216a' 
  AND token = 'O6eqZCw7bNZdf+Musz9Xh29bFRd91eZsGglHH6CRseA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}