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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6b2b82332b02e17866ef0e818a42361a3ac3c4cc1929128308206dced577b9' 
  AND token = '3bSo/2MM4OvYIsnkQjeVAMStJaKZHiPWojOgoT8Q+dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}