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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb3a1b27b226353b21bcb93e427a1268ebbf273448bf6713f8d8b095efc6b52' 
  AND token = 'MCCulLar3qI+oTxJOkNkdyONrljkOHYyu0bf87PJBe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}