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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d8811d8e3255c47133c394d0c15685e863905f916c2ace2d11766de937136d' 
  AND token = 'CHZ0aF9W3j/I3d1stX8KskN7ghhjlFtzTeThA8wC8hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}