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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22788f5f90f7f044831dd4fc8fb22445bb217807143e4198f3f17c28c0e9aa1c' 
  AND token = '0djyylBgtLtWQWUc/v0uJzpasTNCJQK+7zfg7WRhf24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}