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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef640082ffb43a2f5e82992e4b50957d622541f62e77b8b1b12e2dfb33a703f1' 
  AND token = 'qsXCcEUxCrBoGScJ8EN2rh5XdVJMT0rokntQ+Z2zNlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}