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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d974b4b34b67e7e76d9beb188138f12a76baab3da3b2a7dc07c4727789e59a4' 
  AND token = 'BBVtuHNvfSNNlOuV9JDBNSfCRbYR/FX28QD/q1mq4Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}