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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8df64839d98e5530ab264bbd60251fb9e75c124b951e85d014c56808124a2ee' 
  AND token = '46bXwus+pDk6h8S7nhjR4mF3y3P88D41IfCZLiT+fnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}