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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8949e8df1b307e57c914e8ad250a1e162b5acefa932f8fde5bde223272a27d1c' 
  AND token = 'Y6F8rAHd+RWM+eREX3tmUHwbXrqe4OEV4ObuhNMLfW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}