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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3558f5e19609bc422536f52ee6b942df73cc815d429a13c38e6c9f18468bf1d' 
  AND token = 'DeH8EcwKqXNtS07cvqxXNRD6WQT7iE/KR4NcUr8vN4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}