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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9065b670a6cfb86086aae67afe2ca05263ceb65d7ec554f24e0acdb9f2296d92' 
  AND token = '6qTrHND0MQSd5Kc/BrWuvBkrY+q8VZ0AqTqk9qp/t0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}