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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7a4e53d6eca2a7f0b697964486e27ae584d69d85fb7f8699e0740be3d1656b2' 
  AND token = 'DqlYmtK4U1Z8S3PZ7affH0XvSmADndC8zxvIAL2410Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}