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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd357fd4a5b0001eace0e9b756c42c1dc37cb624670569f6a35ba33f8f1b5342f' 
  AND token = 'QApH0Foeh0vRmyyRX0OS5pfYQH2o4u6Bx1yLOML6Xdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}